The Ultimate Guide to Women’s Hormones: Use Science to Reset Your Body, Balance Mood, & Feel Amazing
with Dr. Jessica Shepherd, MD
Today’s episode is your ultimate guide to fixing your hormones at any age—and it’s a MUST listen for every woman in your life.
If you’re tired, bloated, gaining weight in places you never used to, struggling with thinning hair, acne, brain fog, low sex drive, mood swings, PMS, painful periods — this is not how it has to be.
Mel sits down with top OB-GYN and hormone expert Dr. Jessica Shepherd, MD to unpack the science of women’s hormones in a way you’ve never heard before.
This is your science-backed step by step guide to balancing your hormones for health, happiness, and longevity.
Whether you’re 25 or 65, you’ll finally learn how to work with your body, instead of against it, to feel your absolute best.
Wow, I think I hear somebody hitting share right now and sending this to their mother.
Jessica Shepherd (00:00:05):
Hormonal health represents who we are as women, and the more that we vilify it or kind of fight against it, then that's not ultimately helping who we can be in our best version of ourselves.
Mel Robbins (00:00:16):
Today's episode, it is the ultimate guide to understanding and optimizing women's hormones for better health at all ages. Our guest today is world renowned OB GYN, Dr. Jessica Shepherd. She's here with the answers you need if you have really bad PMS. What does that tell you? As a medical doctor,
Jessica Shepherd (00:00:38):
When women come in, I always like to
Mel Robbins (00:00:41):
Can you speak to a person listening who comes off birth control? What do you want them to know?
Jessica Shepherd (00:00:49):
I want them to know that,
Mel Robbins (00:00:50):
Wow. Why do so many women in their twenties get hormonal acne?
Jessica Shepherd (00:00:57):
There can be stuff that is due to chemicals that top foods you should eat for good skin. Oh, I think that top foods should be blueberries, nuts, but also,
Mel Robbins (00:01:07):
Hey, it's your friend Mel, and welcome to the Mel Robbins Podcast. I am so excited that you're here. The conversation that you're about to hear is life-changing, and I want to say it's always such an honor to spend time and to be together with you. And if you're a new listener, I also want to take a moment and welcome you to the Mel Robbins podcast family. And here's one thing I wanted to say because you made the time to listen to this particular episode. Here's what I know about you. You are the kind of person who values information that can help you take control of your health and make you feel your absolute best at every single day, no matter how old or young you may be. And if you're listening to this right now because someone in your life shared this episode with you, I just think that's really cool because here's what that means.
(00:01:57):
It means you have people in your life that care about you. They want you to be healthy, and they know that understanding and knowing how to optimize your hormones, that it's critical for your overall health. That's why they sent that to you. And I think that's just really cool that you have people in your life that care about you. So thank you for listening to this. Thank you for being here. I'm so excited because our guest today is going to help us do exactly that, understand our bodies, understand our hormones, and help us optimize them for better health. Dr. Jessica Shepherd is a board certified OB, GYN, who specializes in women's health, sexual wellness, and menopause. Dr. Shepherd completed her medical residency at Drexel University. She also completed a fellowship in minimally invasive gynecological surgery at the University of Louisville where she also earned her MBA. Dr. Shepherd also served as the director of minimally invasive Gynecologic Surgery at the University of Illinois at Chicago before leaving to practice at Baylor University where she's still affiliated today. She sits on the advisory boards for Women's Health magazine, women's health.org, and the Society for Women's Health Research and is the chief medical officer at the healthcare company. Hers, Dr. Shepherd is also the author of the bestselling book, generation M, living Well in Perimenopause and Menopause. So please help me welcome Dr. Jessica Shepherd to the Mel Robbins Podcast, Dr. Jessica Shepherd. I am so excited to meet you. Thank you for hopping on a plane. Thank you for making the time. I cannot wait to have this conversation with you.
Jessica Shepherd (00:03:33):
I'm just doubly excited to be here. You are someone who I've listened to for a long time and the ability to be able to share my little slice of life with you and with everyone here, I love it.
Mel Robbins (00:03:46):
Well, it's actually a very big slice of life and it's an aspect of life that a lot of us don't understand. And so I cannot wait to learn from you. And where I want to start is I'd love to have you speak directly to the person who is with us right now who has made the time to learn from you, and can you tell them what might be different about their life or the life of a woman that they love, if they really take to heart everything you're about to teach us and share with us today, and they apply it to their life, what could change?
Jessica Shepherd (00:04:22):
I would say for everyone who's listening and even myself, I think this is where this really resonates, is I'm going through that journey as well, but why am I here and where do I want to be? And that really is that opportunity of self-care to say, I get to be in charge of myself. And many times we don't take that time to say what is really going on? Because that's when we really start to push away all the narratives and the stories and what society tells us. And that really is this transformation in life, is to take some time, take pause, and say, why am I here and where do I want to be?
Mel Robbins (00:04:59):
Wow. And what I'm excited about to learn from you, Dr. Shepherd, is oftentimes when you realize you don't feel how you want to feel or you're not where you want to be in your life in terms of your relationship to your health or how you feel or your energy or all aspects of your life that you're not quite sure what the problem is. And so I think today is going to be life-changing because you're about to teach us about our bodies and about hormones and the vital and transformative role that they can play. Let's start with just talking about what made you interested in medicine and women's health.
Jessica Shepherd (00:05:43):
Yeah, it actually started from the OB world, right? Bringing babies into the world. And that was so fascinating to me and it's very exciting. And as I was going through residency, still love OB is when I really, that there is this whole scope of a woman's life outside of pregnancy, but when I really started to see women, whether it was in their adolescence or even later on in life, is that there's still so much to be taken care of, that we really have that ability to interact and build relationship with women. And that's where I really thrived. And so that after residency, I actually did a surgical fellowship. I loved being in the or. I love being able to really take something very complex and transform in a way that's helpful for them in the operating room. And then coming back to who are you and how can I help you there?
Mel Robbins (00:06:36):
And how did being a surgeon impact you and lead you to where you are now and the philosophy that you have about medicine and women's health?
Jessica Shepherd (00:06:46):
And most of the surgeries that I was doing, a lot of times it had to do with women in their midlife. And so when they would come into me with their diagnosis, whether that was fibroids, endometriosis, I got to sit with them and talk to them about this diagnosis. But what actually came out in the visit was all the other things that were going on in their life. And so that's where I started to see our physical health has so much more to do with the mind body connection.
(00:07:14):
So they would come in and have a certain disease or something that was going on, and I was like, I know I can help you there because a surgical thing that I know I'm very skilled to do, but what I'm really paying attention to are the other things that you're telling me that's going on with your life and your career, taking care of your kids, your relationship. And that really has so much more to do with how we show up and what we're able to capacitate, what we're able to take in. And that's when I was like, something's going on in this midlife that I need to pay attention to more.
Mel Robbins (00:07:45):
Well, what I'm excited about is that you know, you mentioned pregnancy. You mentioned doing all these surgeries. If you really think about it and in the forward of your book, Dr. Jennifer Ashton writes about the fact that for most women, the first time we truly get proactive about learning about our biology and our body for real is when we either are wanting to get pregnant or we are pregnant. And so we dive into all of it and we track what's happening in our bodies. And then even afterwards, we're tracking what's happening with our bodies as things are changing. When I think about myself and when I first got my period, it sort of came and then I just had to deal. I had to figure out how to use a tampon. I had to figure out how to navigate a swimming pool. I had to figure out that sort of stuff. We didn't have any of the tracking tools or any of that stuff.
(00:08:40):
But it is interesting that a woman's body and health is incredibly elegant and intelligent and designed in this system right around the fertility cycle and the menstruation cycle. And honestly, most of us don't understand the role that hormones play at all.
Jessica Shepherd (00:09:03):
Not at all. I think pregnancy, you said it perfectly there is that's what society tells us what our worth is in the reproductive years. But even as you said it in your experience, which was similar to mine as far as getting your period, you're just kind of like, okay, I'm going to figure this out.
(00:09:17):
But that was something that had to do with just self, right? Yes. But no one was really paying attention to that. But when it came to now you have to take care of someone else, society's like, here's your importance. And then we dive into it because kind of feeding into that, not to say that pregnancy is important that we don't love it, but now we're fascinated and kind of giving more towards, because we have to take care of someone else when we didn't even choose to take care of ourselves earlier when we were going through a transition, which is why I always see this with my patients that come in is that they're like, now that I've kind of finished that phase of my life, no one's really paying attention anymore, and society's kind of deemed me maybe not that important. So that's where I want women to pay attention to their worth.
Mel Robbins (00:10:00):
Yeah and I'm so excited to dig into the role that hormones play in your health. And on that point about women really thinking about this. And if you are listening and you're one of the millions of guys that listen to the show, this is a really important conversation to listen to because it's going to help you understand the women and young women in your life, but it's also a resource that you can send to them because women are not little men that what Dr. Stacey Sims loves to say And understanding the unique physiology and biology is critical. And we're going to talk today about how hormones impact your skin and acne and hair and thinning hair and growing hair in places that you don't want, how hormones impact all kinds of health conditions. And what I find to be very exciting is that finally, we're at a moment where there is a lot of attention and education around menopause, but that's like 50 years into a woman's story, truly understanding the role that hormones play what they are. It impacts every aspect of your life. And one other thing that you made me think about is that when I think, for example, just one human being ago, so just think about our moms. How old are you?
Jessica Shepherd (00:11:20):
I am 47.
Mel Robbins (00:11:21):
Okay, great. So I'm 56. If I think about our moms, they typically grew up in a generation where the messaging, at least in the sixties and seventies, was, okay, you got to do it all. You got to look good. You got to also keep the house together. You got to be able to take care of everybody. There was zero messaging about taking care of yourself.
Jessica Shepherd (00:11:47):
Oh, no. That wasn't part of the memo.
Mel Robbins (00:11:48):
No. And in fact, if you look at any of the marketing and advertising television shows that our mothers watched, there was no one helping them. They just had to do it all themselves. And so no wonder our moms neglected themselves. No wonder, we don't really understand that putting ourselves first is really a skill that you need to learn. And society has conditioned us to think, oh, no, no, no. Go see a doctor when you're sick. Oh, no, no, no. I have a friend that has prolapse right now. It literally feels like, which is I guess what, when your uterus is falling,
Jessica Shepherd (00:12:24):
Yeah, things are kind of coming out.
Mel Robbins (00:12:25):
Things are coming. One of my relatives had it. They would literally be like, it's walking around with half a baby coming out of you. And I'm like, you are walking around. You should go see a doctor.
Jessica Shepherd (00:12:36):
But that's taking care of self, and we're not trained to do that.
Mel Robbins (00:12:39):
And so let's just start by talking about hormones. How do you want to frame the conversation around hormones?
Jessica Shepherd (00:12:45):
I think hormones are these beautiful complex messengers. So it's like we have these little male men that are, or male women going around delivering messages every day. They are consistent. They know what they're supposed to be doing, and our bodies are beautiful machines and they're meant to be. Well, oil machines with these messengers giving off these messages, whether it's to an organ, the brain or the ovaries, hormones are probably one of the most important parts of how our machine runs.
Mel Robbins (00:13:15):
So is it like a liquid? What is a hormone? You know what I'm saying? Because as you're thinking messengers, I'm like, wait, is it the wiring is is it liquid? What actually is a hormone?
Jessica Shepherd (00:13:24):
Of a, we should go inward and talk about these hormones, but it's actually the delivery of a kind of chemical.
Mel Robbins (00:13:32):
Okay,
Jessica Shepherd (00:13:32):
Yeah. It's a chemical that's released and from these messages that are being sent, then someone can respond. So it's like I'm giving you a message and you're supposed to be doing this today at this time. And so as we go through our lives, we usually through our younger years and our reproductive life, have these hormones that are giving off these messages and they're just going like clockwork. They're like, I know where I'm supposed to be. I know what time I'm supposed to go off. And then we start to see that the hormones have little glitches. They don't want to show up to work. Some of the messages aren't being delivered. And that's where we start to see those changes in fluctuations, which is why exactly, like you said, we need to be having these conversations about hormones earlier so that we're aware before they just kind of capoot and they're out.
Mel Robbins (00:14:16):
Well, you know what's interesting is that if you really think about the experience, whether you are male or female is when puberty hits, the only thing that you hear from adults is, oh, hormones. Oh, the hormones are raging. Oh, here it, and nobody understands what it actually means or what the hormone is doing. When you get to puberty though, and the quote hormones start going crazy, are you not born with this level of hormones? You know what I'm saying? Why are hormones going crazy during puperty?
Jessica Shepherd (00:14:52):
Yes. Because they are now getting the response of we now biologically want to start to deliver our follicles. So we're born with the amount of eggs that we'll ever have, but the delivery of when they're going to release every month starts at a certain time because our bodies are, again, beautiful machines, which they know when they're going to start this process. So in the ramping up for this actual delivery of guys, we got a job to do. We got a new design of a job that we have to start. Everyone's running around, where am I supposed to be? Okay, you're there. Okay, wait, am I supposed to be doing this? And over time, which is when you start to see that fluctuation, everyone's getting ready for the job, and then finally they're like, we've got it down. We've done enough rehearsal. We're ready to do the job.
Mel Robbins (00:15:38):
Okay, I think I've got, and I hope as you're listening or watching, you kind of have this understanding of messengers number one that are delivering a particular message and that your body has receptors all over it that are designed to receive the message from the hormone.
Jessica Shepherd (00:15:54):
Yeah. It's receiving delivery and receiving is the most important part, I would say, of a hormone because they want to get that message across and then the hormones that disassemble. So the job now is kind of falling apart, is what's happening in perimenopause and menopause. What do you disassemble? Well, when we go through a hormone decline, which is the opposite of what we're doing when we're getting towards puberty and adolescence, perimenopause is they're like, biologically, we're not going to be doing that delivery system anymore. We're going to slow down this project now. And people are like, okay, well then I'll come off here. I'm just not going to show up to work anymore. And that's when you start to see the fluctuation of what happens to hormones in the perimenopausal phase. So they're kind of saying, that job that we used to do for 30 plus years of giving off an egg at a certain time every part of the month, we're not really doing that anymore. So that's when you start to see the offloading of what happens with hormones, which is why we now experience all those symptoms in perimenopause.
Mel Robbins (00:16:53):
Got it. And does the same thing happen to men if they experience low testosterone?
Jessica Shepherd (00:16:57):
They do, but their decline is much slower over a longer timeframe, and so that's why you still can have men who are in their seventies and eighties still being able to have or contribute sperm and you get pregnant, but we no longer can after a certain age, which is why women experience menopause.
Mel Robbins (00:17:17):
Gotcha. Okay. So I would love to break down each time period in a person's life and kind of understand exactly what's going on with your hormones and what hormones matter the most during that period of time. What are the key hormones that you need to actually understand are important and play a role in your health?
Jessica Shepherd (00:17:49):
Well, all hormones for men and women obviously play that specific role, but when we speak to just women and how they're going to experience life, I think that's the best way to frame it is how are you experiencing life? What's contributing to the factors that really are kind of key and specific to women? I would say estrogen, progesterone, and testosterone as well as our thyroid hormones. But men do have thyroid hormones as well, as well as estrogen and testosterone. We just have it in different levels. But for women, I would say estrogen, progesterone, testosterone, and our thyroid hormones.
Mel Robbins (00:18:21):
And can we group the thyroid hormones together or are there a bunch of 'em or?
Jessica Shepherd (00:18:25):
We can. They're kind of like cousins, so they're kind of like in separate pods, but they're kind of in the same neighborhood and really contribute towards each other, but estrogen, progesterone, and testosterone.
Mel Robbins (00:18:34):
So estrogen, progesterone, testosterone.
Jessica Shepherd (00:18:36):
Yeah.
Mel Robbins (00:18:37):
Now we hear a ton about cortisol and serotonin, and that's a hormone, right?
Jessica Shepherd (00:18:44):
Yeah. Those are hormones.
Mel Robbins (00:18:45):
And some other ones who I now can't remember, but are they as important
Jessica Shepherd (00:18:50):
They are important.
Mel Robbins (00:18:51):
For understanding when it comes to women's health or is it important for us to just start with estrogen, progesterone, and testosterone?
Jessica Shepherd (00:18:58):
I usually like to categorize it as maybe if we were to say our menopausal metabolic and mitochondrial hormones. And so cortisol is really, I like to put it in the metabolic kind of family of when we talk about hormones because it has such a broad impact on our entire body system, whereas,
Mel Robbins (00:19:15):
And what does metabolic mean?
Jessica Shepherd (00:19:16):
So metabolic means the things that function in how we regulate the activity of our entire body. So metabolically, we would say if you have metabolic hormones that are being shifted, that's usually when we talk to insulin and glucose and how our body is able to absorb glucose, utilize glucose as a fuel. So cortisol really has a lot to do with that as far as metabolic functions.
Mel Robbins (00:19:39):
Okay. So we're going to shove that to the side.
Jessica Shepherd (00:19:41):
You can shove that to the side
Mel Robbins (00:19:42):
And we'll stay right here with estrogen, progesterone, testosterone, and let's start with puberty.
Mel Robbins (00:19:47):
What is going on when puberty hits for a young woman? What is the general age range at this point, and what are the roles that those three hormones play for a woman?
Jessica Shepherd (00:20:02):
So I would definitely say what we have started to see over the last few decades is typically when we start our period that age has become younger.
Mel Robbins (00:20:11):
Why?
Jessica Shepherd (00:20:11):
And so that age has become younger because of environmental factors. A lot of the things that we have in our environment, a lot of the foods that we eat. So it actually is something that we should be researching in a way of why is this happening and is this something that has implications on our life later on? And when I say later on your fifties, and I would think so, absolutely. Why? Because cortisol, which we kind of bring it back into the conversation a little, has a lot to do with, is this the reason why we're starting to see our women or young girls starting to have their periods at a younger age? And so what's happening is you're to have this onboarding, right? We talked about this complexity of our bodies and the systems and how it's being regulated. So the onboarding time is a little bit earlier now, and so what's happening is that estrogen is starting to rev up because our bodies want to release this egg in order to have a menstrual cycle. And so it starts that process earlier in estrogen and progesterone. Are there going to be those key hormones that are going to filter into when am I going to be high? When am I going to be low? Right? We talked about how they're coming into themselves as a system and a bodily function in order to accomplish an event, which is your menstrual cycle.
Mel Robbins (00:21:24):
So what is the role of estrogen?
Jessica Shepherd (00:21:26):
Estrogen, really, I like to call it our vitality hormone because we really see, when we look at our menstrual cycle, or even when women come to me and they have changes in their menstrual cycle, we typically like to say, how is estrogen functioning and as a vitality hormone, what is it contributing? Maybe it's a little bit too much here or a little too little, and how can we alter it in a way where you can get back to maybe your normal rhythm or your normal menstrual cycle? So it builds up when we're starting our period, and it really is creating your body's in default actually to get pregnant, which is the whole reason for your menstrual cycle is to conceive and to get pregnant.
Mel Robbins (00:22:08):
Is it important as a woman to understand that your entire health and the way to think about your health, you really have to embrace that the natural intelligence of your body, the baseline is it is designed as a baby making machine.
Jessica Shepherd (00:22:31):
I would say biologically. That's what, if we were to look at it just from key framework,
Mel Robbins (00:22:37):
Just I'm just literally just like your tongue is designed to taste.
Jessica Shepherd (00:22:41):
Absolutely.
Mel Robbins (00:22:41):
Your legs are designed to move in a certain way that you are designed with sort this biological imperative. And I'm only saying that, you know what I mean?
Jessica Shepherd (00:22:51):
It's designed biologically to do that function.
Mel Robbins (00:22:54):
Yes.
Jessica Shepherd (00:22:54):
What I want to make sure that we understand is it doesn't necessarily mean that we have to do that.
Mel Robbins (00:23:00):
Oh, of course.
Jessica Shepherd (00:23:01):
Right?
Mel Robbins (00:23:02):
Of course.
Jessica Shepherd (00:23:02):
But I think that society does teach us that that's what you're designed to do and that's what you're supposed to do.
Mel Robbins (00:23:07):
Yes. The reason why I'm kind of taking a highlighter to that is because we know that of course, because you have a period that you have to deal with. But if you really start at a baseline and you say to yourself, okay, women are not little men and our bodies all the way down from chromosomes to the way our muscles are to the way the hormones work, our bodies are completely different. Understanding that it is designed to work on this cycle and the cycle is driven by hormones, is the base of all health. Correct?
Jessica Shepherd (00:23:44):
And would say that once you understand that, then you can embrace it for what it is and not fight it and work with it and work with it and not work against it.
Mel Robbins (00:23:52):
Okay. So before you get your period, this is going to sound like the world's dumbest questions. Do you have estrogen? You know what I'm saying like is this stuff in your body?
Jessica Shepherd (00:24:01):
Everyone is born with the amount of hormones or the hormones that we have, how they function changes during the life cycle.
Mel Robbins (00:24:08):
Wait, you are born with the amount of hormones you have?
Jessica Shepherd (00:24:11):
Well, not the amount, but you have the hormone.
Mel Robbins (00:24:13):
Okay, gotcha.
Jessica Shepherd (00:24:13):
How they function changes over the course of our lives, which is why we see those changes at adolescence and then perimenopause.
Mel Robbins (00:24:21):
Gotcha. So even before you have a period, you still have estrogen, testosterone and progesterone in your system. It's that when you start getting your period, those hormones flood into the system in order to bring this developmental phase online.
Jessica Shepherd (00:24:38):
And that's why I love the body. It is so complex, but so elegant because it was always there, but the need for it to do the job that it was designed to do at that time in your life, that's when it knows I need to start doing this. So it's the onboarding, but that's what I love about the kind of basic fundamental part of the body, and that's why we should embrace every part of our lives.
Mel Robbins (00:25:01):
So you said that the average age is getting younger and younger, and one of the reasons is the food we eat
Jessica Shepherd (00:25:10):
Environmental
Mel Robbins (00:25:10):
And ultra process foods
Jessica Shepherd (00:25:11):
cortisol and cortisol as well. Stress, and that's where cortisol is our stress hormone and it responds to stress. And so when we have stressors that are showing up early in our lives, a lot of it has to do with the experiences that we have, environmental factors in food. Then that's why we're starting to see that girls are starting to have their periods much younger.
Mel Robbins (00:25:33):
Is that because cortisol confuses the design of the body in terms of when it's time to bring this online, or is it the food?
Jessica Shepherd (00:25:44):
It's more so that the cortisol is responding to these stressors and then onboarding much too early or much too high of a level than when it's supposed to.
Mel Robbins (00:25:54):
Oh, gotcha.
Jessica Shepherd (00:25:56):
Yeah. It enters the scene when it shouldn't be, and we're like, you're not really supposed to be appearing at this part of the script, but you're here. And so now we were going to respond to you.
Mel Robbins (00:26:05):
Gotcha. So what are some of the issues that happen during that window? Because I can think about, it seems like so many young women also now have complicated cycles, whether it's lots of cramps, and so what are the roles that estrogen, progesterone, and testosterone are playing in that window in the teenage years up to 20?
Jessica Shepherd (00:26:29):
So the roles that they're playing is getting the body ready for this now 30 year or maybe 20 year thing that they're going to be doing.
(00:26:37):
So that's when you start to see the breasts enlarge. You start to see hair growth, you start to see changes in the external genitalia, and that has a lot to do with how the hormones are responding. It's getting the body ready and also to do the thing that we talked about to get ready for pregnancy, and that's what the body has the capacity to do in your reproductive years. And so that's when women start to see changes in their moods. I mean, how many times have you heard adolescent girls and going through puberty again? Yes, that mood is there because our neurotransmitters, which are also hormones, are responding to these changes when we start to onboard our estrogen, progesterone, and testosterone to do the function of the period.
Mel Robbins (00:27:17):
So when you move into your twenties, what's going on with hormones?
Jessica Shepherd (00:27:23):
Hormones are at this point, should be functioning very consistently. We know what our job is, we're having a cycle. We may get pregnant, go through the pregnancy, repeat baseline, what we're doing again. So that's when it should be kind of, we should be okay. This is typically when women might start to come in with issues with maybe pain with their cycles or maybe heavier cycles.
Mel Robbins (00:27:48):
Yes.
Jessica Shepherd (00:27:49):
And so it really should be kind of even keel during this timeframe, but that's not what we always see.
Mel Robbins (00:27:54):
So if it's not even keeled, meaning a pretty regular cycle and a pretty predictable kind of route of these are the days I'm kind of moody or grumpy or whatever. This is the days I kind of get those weird cramps. But if you have an irregular period or you have heavy bleeding or you have really bad PMS, what does that tell you as a medical doctor?
Jessica Shepherd (00:28:19):
When women come in, I always like to peel the layers back because that's very subjective and subjective, meaning everyone has different experiences.
(00:28:29):
What are their tolerance to that experience? What's going on in their life? How do they deal with stressors? And I'll give you an example, and this is where I love the beauty of these conversations is to always recognize that everyone has a different template and everyone has a different experience in life. A lot of my women, especially women of color who come in have different stressors because of what's going on in their environment, whether that's racism, whether that's poverty, whether that's increased stress or that's the cortisol. A lot of what they're experiencing is a lot different to women who are not in those particular environments. And so that's part of peeling the layers back, especially as a physician when women come into me is not looking at just the issue that's going on is saying, what else is going on in your life? And that's the mind body connection. And so when we are able to look at those factors versus maybe it's a food issue, there are a lot of foods that can change how our hormones respond,
Mel Robbins (00:29:26):
Like what foods change, how your hormones respond?
Jessica Shepherd (00:29:27):
So your processed foods, your foods that have high glycemic index that have a lot of sugar, a lot of soft drinks. I do see a lot of my patients who are in that timeframe when I look at their diet, I'm like, let's start here. For me, that's a lifestyle change that can impact you greatly. And I don't necessarily have to put you on a medication, so that might be a better way of looking at it. And also with exercise. Exercise does have a beautiful way of releasing other chemicals and hormones in our body that can help regulate our period, but we have to utilize that. Then also stressors. What's going on in your life? It's notorious for stressors. Women come in and they'll say, I'm having all these changes in my cycle, whether it's heavy or lighter, irregular doesn't matter. I will always ask them, what's going on in your personal life? What's going on in work life? Again, when we have that session, that's why OBGYNs are actually usually said that they're also psychologists because we absorb a lot of what's going on in their life when they come in for a visit.
Mel Robbins (00:30:24):
I think it's fascinating that stress in your life and the food that you're eating impacts the hormones in your body.
Jessica Shepherd (00:30:33):
Categorically. And I will say that emphatically because our lifestyle and how we conduct our lives on the outside with those factors of food, nutrition, exercise, really does change the game. And that's why we are starting to see when we get into later life or even in midlife, that is also a very important part of what your body's going to be able to do. Your body can only do what you give it, and if we're not giving it the things that it can thrive, then that's when it's like, I may not be able to perform at my best ability.
Mel Robbins (00:31:07):
Where exactly is estrogen made? You know what I'm saying? So I'm starting to think now. Okay, now wait a minute. So I mean, it makes sense that if you're going through a breakup or you're a person who is subjected to chronic bias and racism or you're under a tremendous amount of stress because you're caring for somebody or you're just constantly eating terrible stuff, I think about somebody that I love deeply who had a very big issue with an eating disorder and just destroyed their gut health, and I can't even imagine the kind of stress that they put themselves under. I mean, of course it would impact your, when you explain it that way, Dr. Shepherd, it makes a lot of sense, but why do these things impact estrogen and progesterone and testosterone?
Jessica Shepherd (00:31:57):
I'm so glad you asked this question because what does it have to do with the mind? Because the brain usually is the control center for a lot of hormones.
(00:32:06):
So it is the one that is going to tell the ovary, I need you to give off a little bit of estrogen today. We're going to give off this much. We're going to dial it down on this day because we're getting ready for ovulation. All those different messages are usually generated from the brain. So imagine what happens with our neurotransmitters when we undergo stressful situations, whether it's something that happens when you're crossing the street and you almost run over by a car versus exactly what you said, a stressor in life that's really taking over all your thoughts, your everyday life, that your brain can respond to that in a way where it's trying to help you cope with that stress. But what happens is when we have stress, the brain can't give off the message to all the other hormones in the way that it could when it wasn't as distracted. And that's why we have to, as physicians get better at mind body connection.
Mel Robbins (00:32:58):
It makes so much sense. And what's sad is your period gets irregular or you start having massive cramps, and then you think that you need some medication and you're not looking at the underlying factors because I never understood that stress or eating ultra processed food or basically starving myself to be skinny is going to of course, impact the hormonal functioning of my body, confusing it with all these things.
Jessica Shepherd (00:33:28):
Yeah.
Mel Robbins (00:33:28):
Why do so many women in their twenties get quote hormonal acne?
Jessica Shepherd (00:33:34):
Yeah, hormonal acne. Again, when we think of there's different types of acne, just there can be stuff that is due to chemicals that maybe you're using on your face that are not the best, but usually a lot is hormonal, and you can actually sometimes tell by where it is on your body where you're getting, yes. So most hormonal acne can be mostly in the area right under the eyes or the chin.
Mel Robbins (00:33:58):
Why does it go there?
Jessica Shepherd (00:34:00):
Because when we're thinking of where the hormones, you have receptors all over your body that respond to hormones, and so the receptors that maybe respond more to estrogen or testosterone's going to be features on or areas on your face that are going to be more prone to the actual area of the breakout. And so when we think of what kind of spurs on these changes in hormones, which will then trigger hormonal, a lot of it has to do with testosterone. Testosterone has a lot to do with sebaceous glands. So a sebaceous glands are the ones on all parts of our body that hold the oil because we need oil, your face, this is how our body functions. We need oil secretion. But when there's a buildup of those areas, and in the glands can be an increase in testosterone as well, which then elicit the buildup of oil, which then you get bacteria and then you have acne.
Mel Robbins (00:34:47):
Wow.
Jessica Shepherd (00:34:47):
Yeah.
Mel Robbins (00:34:48):
And so do you see this a lot with 20 year olds?
Jessica Shepherd (00:34:50):
I do. They come in and usually what is the best way to treat them? So it's a great relationship we have with dermatologists because they'll have these patients come into them, and a lot of dermatologists will actually send the patient back to an OB GYN, because typically we will put them on birth control pills to kind of help quiet down this kind of overwhelm of hormones, and it responds to that. And a lot of it has to do with the testosterone feature of what's being elevated, what's creating that message being sent, and then you have the outcome of the hormonal acne.
Mel Robbins (00:35:23):
Wow.
Jessica Shepherd (00:35:24):
Yeah.
Mel Robbins (00:35:24):
Can you speak to a person listening in their twenties or thirties who comes off birth control and then has a lot of issues after? What do you want them to know?
Jessica Shepherd (00:35:38):
I want them to know that the body is really trying to get to homeostasis. And homeostasis is just that kind of perfect balance that the body needs to be able to do the functions that it wants to do. Now when we're on birth control, the goal of birth control is to somewhat suppress or kind of decrease the activity of your hormones that your body naturally produces. And when it does that, it is doing the job of what it's supposed to be doing is preventing pregnancy by decreasing the suppression or rather the release of an egg. Your body's in default to get pregnant every month, so it wants to release an egg.
Mel Robbins (00:36:15):
So what happens to all those hormones in your body if it still,
Jessica Shepherd (00:36:18):
They're still there, they're still doing what they're supposed to be doing, but the birth control is kind of keeping it a little bit more suppressed so it can't do the function it wants to do. So when you come off now you're lifting off this veil that was always there and suppressing, so now your hormones are like, we can go back to what we were doing. And it's trying to find that homeostasis. And sometimes you might have highs, sometimes you might have lows.
Mel Robbins (00:36:44):
So what might somebody expect and what would you say? Dr. Shepherd is a good amount of time to give your body to like, ah, okay, what's happening here?
Jessica Shepherd (00:36:58):
Immediate gratification is usually what we want when it comes to our bodies. And I always am coaching my patients to give their bodies grace. And when I say that in a timeframe that may be three to six months,
(00:37:11):
I've had some patients who may take nine months to a year to kind of regulate and get back to what they used to be. But just after pregnancy, we always want our bodies to kind of be perfect, bounce back like eight weeks after, but our body doesn't function like that. And so even in the perimenopausal phase, going through these changes, we need to give our bodies more grace and time to do the thing that it's designed to do, but we can't push the agenda as quickly as we would. So three to six months usually I would say give it that timeframe, and when they come back in, I'll be like, well, where are we? Because remember, it's a gradient. They may see that they're improving over three to six months, but maybe not getting all the way back to where they were, and so maybe we can push out time a little bit more.
Mel Robbins (00:37:55):
Okay. And it's interesting, I think about the fact that so many young womeng go on birth control and you do it for a number of medical reasons, which I am in full support of. But is there anything that we should be aware of? If you have been on the pill or you're taking one of the coded IUDs for two decades of your life and then all of a sudden you're like, okay, let's stop taking the pill. Let's take out the IUD and you've been doing this hormone suppression for 15 or 20 years.
Jessica Shepherd (00:38:33):
Yeah, you are going to see changes. And a lot of that has to do with we were not used to seeing what the body was naturally doing for that long. So now when you're exposed to it, you're like, this is off-put, or this is weird, but really the body may be like, oh, I was kind of doing this all along. We just weren't really aware of it because we had some suppression. So that can be changes in how your cycle comes back. People may experience that it's heavier or maybe they're having longer cycles and duration, and that may be because the birth control is kind of not doing what it wanted to do. You also may see changes in skin. You may also see changes in hair.
Mel Robbins (00:39:09):
What changes do you see in hair?
Jessica Shepherd (00:39:11):
So hair, you can start to see that maybe they're going to have more thinning or falling out of their hair because it's the shift in the hormones. So it's not that there's something wrong all the time.
Mel Robbins (00:39:21):
It feels like it's wrong when literally like a dust ball on the drain.
Jessica Shepherd (00:39:25):
When there is a clump of hair in your hands. It does feel so wrong. What the body's trying to do is get back to that homeostasis, right so our,
Mel Robbins (00:39:32):
But why are you losing hair?
Jessica Shepherd (00:39:34):
Because it's the shift. So you were suppressing your hormones with this birth control, and now that you're lifting it off, it can skyrocket back to what it wanted to be, right? It's like, oh, well, no one's kind of keeping me down. I'm going to come out. And the hair cycle is impacted by hormones. So how our hair goes through cycles and phases of growth, when it falls out, when it's going to be what it wants to be within the cycle, those can all change due to what our hormones are telling it. Right? Hormones are chemical deliverers.
Mel Robbins (00:40:06):
So is every single function in a woman's body impacted by estrogen?
Jessica Shepherd (00:40:12):
Absolutely. There are estrogen receptors all over the body. In generation M, there is this, I was like, this diagram has to go in this book because we have typecast, estrogen and progesterone just to the pelvis. Just to the pelvis.
Mel Robbins (00:40:25):
It's true. I think about estrogen, and I'm like, well, it's just talking to my ovaries. What are you talking about? Why do I?
Jessica Shepherd (00:40:30):
I know it's talking to your brain. It's talking to your muscle, your heart, which is exactly why we see when estrogen goes down after menopause, what do we have? We have heart disease. Our bones are weaker. Our brain goes through this fog, and that's because estrogen is estrogen, receptors are there. So if it's not able to deliver the message, then that area of your body is like, I'm not going to function the way that I used to or would like to because estrogen is not there.
Mel Robbins (00:40:58):
What is a few places in a woman's body that somebody might be surprised to hear has estrogen as a very critical piece of how that part of your body functions?
Jessica Shepherd (00:41:12):
You know what I say is the most fascinating is the brain. And why? Because even as an ob, GYN, it's like you know it, but you don't know it. I don't think I realized how much of an impact that estrogen makes on the brain until maybe five, 10 years ago.
Mel Robbins (00:41:28):
So what impact does it make on the brain?
Jessica Shepherd (00:41:30):
It has an impact on mood. It has an impact on cognition, how we're able to function, how we're able to use our prefrontal cortex. We become more limbic in our responses. What does limbic mean? Limbic means that emotional, right? Oh, yes. That kind of jump to the right. And what do we hear that women who are in their perimenopausal phase are more moody?
Mel Robbins (00:41:49):
Well, that's also what we hear about PMS.
Jessica Shepherd (00:41:51):
Absolutely.
Mel Robbins (00:41:52):
So is PMS like a mini drop in estrogen in your body?
Jessica Shepherd (00:41:57):
It's a drop. So it's the fluctuation. It may go down then come up really quick, but unfortunately in perimenopause it's going down, but it's not really coming back up. It's like, I'm really going down and I'm not coming back up. And so that's why you start to see in between the ages of 45 and 55, we have the most diagnoses of anxiety and depression. It makes so much sense.
Mel Robbins (00:42:17):
Wait, hold on. You see the most diagnoses of anxiety and depression in women between the ages of and midlife women, 45 and 55?
Jessica Shepherd (00:42:25):
Absolutely.
Mel Robbins (00:42:26):
Why Dr. Shepherd?
Jessica Shepherd (00:42:27):
Because this is when estrogen, our key response, our key hormone in how it interacts with the brain is going to be impacted because our mood, our neurotransmitters are dopamine After menopause. We start to see that dopamine receptors are 30% less, and so if that's our hormone that's going to be around to make us feel good, and now it's not there anymore, what do you think is going to happen? And so this is why it's so crucial that people understand the mind body connection is so important and you are not alone during this journey. You are not the only one who's experiencing this. And the more that we can look inward and say, I'm going through this, I'm going to be okay, but I also understand why wouldn't that make someone feel better?
Mel Robbins (00:43:13):
Of course.
Jessica Shepherd (00:43:14):
Absolutely,
Mel Robbins (00:43:14):
Of course.
(00:43:15):
Because you can't solve the problem if you don't know what the problem is.
Jessica Shepherd (00:43:18):
You can't.
Mel Robbins (00:43:19):
And if you are starting to experience higher states of anxiety or you're feeling depressed and you're not looking at the correlation with your age and understanding that by 45 a lot of the estrogen is gone and your body's going through major changes which impact your brain, which literally can be the cause of this happening in you.
Jessica Shepherd (00:43:45):
Do you see how it impacts careers? It impacts relationships,
Mel Robbins (00:43:47):
Of course.
Jessica Shepherd (00:43:48):
Your personal life, yeah, you're feeling you're going through just like this. And that's what women used to come in and tell me because they couldn't put their finger on it. They would say, I don't feel right. Something's off. I feel like I'm just so emotional. I can watch TV and cry to commercial. Or someone can say one thing to me and I will snap. And they feel as if it's an outof body experience. They're literally watching themselves have these responses.
Mel Robbins (00:44:14):
Well, it kind of is because you are out of the body you have been living in for the last 40 some years because the hormones are radically changing, and so your body's probably like, what the hell is going on? Can you explain how estrogen starts to decline in your late twenties and what are the big general age markers, Dr. Shepherd for when you got a hundred percent of this, if things are working well and you're not eating too much processed food and you're managing your stress and you're taking care of yourself, which a lot of us just assume that you're kind of like the one that's doing it right on the planet. What age, Dr. Shepherd, do you start to see estrogen decline or progesterone or testosterone in women?
Jessica Shepherd (00:45:06):
Mel, this is why this conversation is so important for a 20 and 30-year-old. So let's bring it back to the reproductive phase, right? Yes. So our body's designed to do this. We know in the reproductive phase as OBGYNs, we start to see a change in a decline in egg quality and the ability to get pregnant spontaneously after the age of 35.
Mel Robbins (00:45:23):
Okay.
Jessica Shepherd (00:45:24):
Now, why do you think,
Mel Robbins (00:45:25):
Oh, because estrogen starts to fall off a cliff.
Jessica Shepherd (00:45:29):
Yeah.
Mel Robbins (00:45:29):
Is that right?
Jessica Shepherd (00:45:29):
Yeah.
Mel Robbins (00:45:30):
Does testosterone and progesterone also change in a woman's body at the age of 35?
Jessica Shepherd (00:45:34):
Estrogen and progesterone, which impacts what we're able to do with releasing that follicle. So our chemical messenger is not able to tell the ovary we're going to fire off a egg as readily. So it's like, I'm not doing it this month, or the quality of the egg not really going to be that great. Then testosterone is also taking a decline, although it is more subtle, but that's where we start to see that drop in estrogen, which is some women, especially I'm one of them who had kids later on in our age, I think,
Mel Robbins (00:46:01):
What is that awful term that they use?
Jessica Shepherd (00:46:03):
They use geriatric pregnancy.
Mel Robbins (00:46:05):
Yeah what the
Jessica Shepherd (00:46:06):
Who came up with that?
Mel Robbins (00:46:08):
Clearly not a woman.
Jessica Shepherd (00:46:09):
Not a woman. And so even I start to see a lot of my patients having kids later on in their life, what happens is usually after they deliver, they start to experience the perimenopausal kind of symptoms. Hot flashes, night sweats, mood changes kind of entered into that phase just very quickly after delivering their children.
Mel Robbins (00:46:29):
Wow. So at 35, do you know the percentage roughly of how much estrogen kind of functioning is left?
Jessica Shepherd (00:46:37):
Well, what we do know is looking from a pregnancy perspective in the ability to get pregnant after the age of 35 versus after 40, and then 42 is another marker when we're thinking of fertility of when it really starts to drop off. And so the ability to get pregnant in your twenties is much more than in your thirties. And then after 35, it does take a drop than again, at 40 and 42 is usually when we start to see another decline.
Mel Robbins (00:47:03):
Wow. Well, it's so helpful to understand this against the backdrop from an evolutionary perspective, what a woman's body is actually designed to do from a physical and biological standpoint. And when you look at it that lens, and you understand, I was researching something else and was kind of gobsmacked to consider that in the 1920s, the average life expectancy in America was 27 years old.
Jessica Shepherd (00:47:33):
Isn't that crazy?
Mel Robbins (00:47:34):
And literally, just like a couple people ago, like 50 years ago, the life expectancy was in our fifties and we've gained 30 to 40 more years in the last five to six decades based on improvements in health and sanitation and medical research.
Jessica Shepherd (00:47:54):
Do you know what? We haven't accounted for that gap in life expectancy with now estrogen still gone, and that's why we still see women living longer. Yes, that's great. I'm all for that. But we're living life in poor quality of health, and we're seeing these health measures of what women typically, they have more dementia, they have more osteoporosis, they have more heart disease. Number one killer of women is because that estrogen was gone, but we're still living longer.
Mel Robbins (00:48:21):
This is so important to understand because I think what we do as women is we throw our hands in the air and say, well, there's nothing. Why is this happening? All this stuff. But when you look at it across the historical perspective and the fairly recent life expectancy jump,
Jessica Shepherd (00:48:38):
So when we look at life expectancy, we know that women typically was used to be 57, 58 was the life expectancy, but what is the average age of menopause? 51, 52. So it makes sense biologically that estrogen is kind of tanked and the life expectancy of what the body's able to do because estrogen is not there
Mel Robbins (00:48:58):
50 or 60 years ago,
Jessica Shepherd (00:49:00):
Is going to be
Mel Robbins (00:49:00):
Not a problem.
Jessica Shepherd (00:49:01):
Not a problem. Makes sense. But now we have improved with science, technology, nutrition, sanitation to our seventies and eighties, but we have not accommodated the body to function without estrogen.
Mel Robbins (00:49:14):
Wow. It's almost like if you have a car and you don't have any gas in it, how is it going to work for you for like 20?
Jessica Shepherd (00:49:23):
You just got to keep driving, Mel,
Mel Robbins (00:49:25):
Just hit the gas harder and stop complaining and it'll work.
Jessica Shepherd (00:49:29):
But isn't that the analogy of what we're told to do? Just keep going. I don't care if you feel crazy. I don't care if your bones are breaking, just keep going. So this allows us, again, to take that step back and have more grace with our bodies, but it's because we now understand the biology of our bodies.
Mel Robbins (00:49:45):
Is there things that you can do in your thirties and forties to slow the breakdown of this hormone decline?
Jessica Shepherd (00:49:53):
There is not, but there are ways that you can help your body do better things. In other words, optimize the ability for the body to do it. Even in the absence of estrogen and progesterone.
Mel Robbins (00:50:06):
Like what are the most important things?
Jessica Shepherd (00:50:07):
I would say nutrition and exercise, because those are fundamental things you can do every day or even if it's four times a week. But those are things that are giving our metabolic health and our mitochondrial health, the best ways that they can function, even in the absence or the decline of some of these hormones. So that's going to be paying attention to decreasing your processed foods, your sugar, because your body just doesn't respond to it as readily as it did in twenties and thirties, which I would not advocate for people just because they're 20 and 30 to eat these types of foods. But then also exercise in weight training to be able to build that muscle up so it can utilize the glucose better so that your body's just not sitting with the glucose.
Mel Robbins (00:50:47):
Do women that have children after 35 tend to enter perimenopause or menopause earlier?
Jessica Shepherd (00:50:55):
It's not necessarily that they're entering it earlier. It's that we do have a significant change of hormones in pregnancy, and what we do see is after pregnancy. So in the postpartum phase, you're going to have that shift again, trying to get back to homeostasis,
Mel Robbins (00:51:10):
Which you have taught us, Dr. Shepherd, you got to give your body grace,
Jessica Shepherd (00:51:13):
Give your body grace
Mel Robbins (00:51:13):
Nine months to a year it could take until you feel like yourself again.
Jessica Shepherd (00:51:17):
So if you think that's nine months postpartum, nine months typically for a pregnancy that's almost like a year and a half timeframe. And so in that year and a half is where you start to see that. Now they're entering into the natural kind of fluctuation on the decline towards menopause. And so it does seem a little jarring or quick, but really the body was already on its way, and now we've kind of distracted our body or ourselves from what was happening because we were pregnant. And then after your body's like, well, I was still going in this direction, I'm going to continue to go in that direction.
Mel Robbins (00:51:47):
So we've covered what happens at 35, 40 and 42. Let's talk about perimenopause, medically speaking, Dr. Shepherd, what does that word mean and what is the kind of typical age range of women that covers?
Jessica Shepherd (00:52:05):
Well, that would be me. I'm perimenopausal proud of it, but perimenopause has been more of a confusing term, I think in what we've seen in this menopause surge, because menopause is very clinical in its definition, but perimenopause is confusing because it can last anywhere from three years, seven years, 10 years, because everyone's different in that decline in fluctuation. But it's truly when our hormones, estrogen, progesterone, and testosterone are starting to go down and shift down and you start to have these symptoms here or there. Some people may not have symptoms.
Mel Robbins (00:52:37):
I mean, wouldn't that start when you're 35?
Jessica Shepherd (00:52:39):
Some people, I have had patients and I would definitely say sometimes I'm like, wow, you are pretty young, but I'm never going to take that experience away from them that they may start to experience symptoms of perimenopause.
Mel Robbins (00:52:51):
So what are the symptoms of perimenopause and what physical changes happen when you are in that zone that I'm just going to put a big hoop here, like 35 to 50 ish. This could be the zone that you're in.
Jessica Shepherd (00:53:08):
This could be the experience and the timeframe. So I would definitely say a hot flashes, a night sweats, kind of here or there. People will be like, did I just have a hot flash? And then you may not feel it again for months. Definite change in weight. I've had so many women who come in and being like, I'm doing the same two mile run. I'm doing the same elliptical for an hour, and now the weight's going absolutely nowhere, irregularity in periods. That's where we start to see lighter, heavier. Now I have two times a month now I skipped three months, then it came back. And a lot of that has to do with that fluctuation. Remember the car assembly line? Some people didn't show up to work that day. They're just like, I'm not doing the assembly line.
Mel Robbins (00:53:45):
Or the car that you've been driving is starting to sputter.
Jessica Shepherd (00:53:48):
It's sputtering.
Mel Robbins (00:53:48):
Yes.
Jessica Shepherd (00:53:49):
And so those start to happen through that timeframe.
Mel Robbins (00:53:52):
Why do we gain weight in the middle? Why do we get the back fat and the fanny pack in the front and all the things that you've been doing?
Jessica Shepherd (00:54:04):
And all the things that you're not asking for, quite frankly,
Mel Robbins (00:54:06):
And the flappy ass arms, you don't have those. But I would have these meat wings. It didn't matter how often I was doing triceps, it still doesn't work. But why did we gain weight there?
Jessica Shepherd (00:54:23):
So we gain for multiple reasons. Again, it's never just one thing. So our fat cells do respond to estrogen. We know that the estrogen receptor is all over the body.
Mel Robbins (00:54:32):
Why respond? Because there's estrogen in every part of the body.
Jessica Shepherd (00:54:35):
So think about when you're pregnant and you do gain weight, that's for a safety reason to kind of cushion the body, to accommodate the pregnancy, right? So fat cells do respond. Actually, I thought it was because I was eating my way through the entire day, baby was been some of the reason, but we can blame it on the fat cells. But there's accommodations into how they respond. So they can shrink, they can get bigger, they can migrate, and then they can usually go back. So typically after pregnancy, a lot of people will go back to the way that their bodies appeared before in perimenopause. That response, remember we said chemical messengers, but if there's no estrogen, the receptor is there waiting for it, it's not responding. So fat cells can enlarge, but maybe they now don't have the capacity to shrink.
Mel Robbins (00:55:16):
Oh wait a minute. So you have estrogen receptors in your triceps and in your
Jessica Shepherd (00:55:22):
In your fat cells and in your muscle.
Mel Robbins (00:55:24):
But there's certain fat cells. I think everybody listening can go, yes, smell. It's true. There's certain, it's like every pair of pants
Jessica Shepherd (00:55:32):
Fits different. So that's the migration.
Mel Robbins (00:55:34):
Different, didn't fit. It's literally, I'm like, what happened? I feel like a twinky on legs here. Like I just it just
Jessica Shepherd (00:55:40):
It migrates. So it goes from your hips and your butt, which is what we see in twenties and thirties where it's supposed to be in that timeframe and then it migrates to that abdominal area, the fanny pack area, because the estrogen is like, well, we're not responding in that way, but we're also going to shift now where the fat cells are. So they kind of migrate more to that area.
Mel Robbins (00:56:00):
Is it because as the estrogen declines your reproductive centers like sucking it all up and then everybody else is starving for it in your body?
Jessica Shepherd (00:56:12):
It's really, it's the biology of the body. It's really what your body is designed to do as we get older, because even men go through that. They don't go through it as I would say, maybe as rapidly or profound women. But you do notice too as men start to age,
Mel Robbins (00:56:26):
They get that, they start to look pregnant. There's a lot of guys is that because of the testosterone that's,
Jessica Shepherd (00:56:31):
But they also have estrogen as well, just smaller amounts. But this is the beauty in what the body is designed to do. It does it, even though we don't love for it to do it, but it does happen during that timeframe a lot to do with estrogen and also our muscle muscle starts to decrease as well. If you think of a pie graph,
Mel Robbins (00:56:50):
Why does our muscles start to decrease?
Jessica Shepherd (00:56:52):
Yeah, so this is again, because estrogen receptors and we're
Mel Robbins (00:56:55):
are in the muscles?
Jessica Shepherd (00:56:56):
Are in the muscle,
Mel Robbins (00:56:57):
And when your muscles are getting estrogen, your muscles stay strong,
Jessica Shepherd (00:57:01):
Right? Well, not necessarily strong. Strong is more of a power kind of force thing, but the actual muscle mass, so the amount.
Mel Robbins (00:57:08):
Wow. So how does keep going, I'm sorry.
Jessica Shepherd (00:57:11):
No,
Mel Robbins (00:57:11):
It's fascinating.
Jessica Shepherd (00:57:12):
Think of a pie graph
Mel Robbins (00:57:13):
Like Jesus. Okay, go ahead.
Jessica Shepherd (00:57:14):
If you think of a pie graph, and maybe most of it was filled out with muscle and a little bit of fat content there in the pie graph, as we start to age, that pie graph shifts and we start to see the fat increase.
Mel Robbins (00:57:26):
I don't want it to increase though.
Jessica Shepherd (00:57:27):
I know, neither do I. This is not what I want either, but the muscle mass starts to decrease as well is the fat mass is increasing.
Mel Robbins (00:57:36):
What's crazy about this is that when you go through it, what I'm getting from this conversation is that the composition of the body itself is changing
Jessica Shepherd (00:57:51):
Absolutely.
Mel Robbins (00:57:52):
Because the hormones have changed. So literally I love that image of a pie chart because if you think of a whole pie and if for a lot of your life as a woman, the majority of it was kind of muscle mass. But then as estrogen declines, that fricking wedge starts to get smaller and smaller and now fats there and you didn't do anything different.
Jessica Shepherd (00:58:15):
He didn't do anything different.
Mel Robbins (00:58:16):
Wow.
Jessica Shepherd (00:58:17):
Yeah. And so we have the ability, you'd asked earlier,
Mel Robbins (00:58:20):
This is not fair, Dr. Shepherd,
Jessica Shepherd (00:58:22):
It is not fair.
Mel Robbins (00:58:23):
Do something. What are we supposed to like help us.
Jessica Shepherd (00:58:25):
Life is not fair. And this is one of those things that you're like, if we could maybe take this part out, but you'd said it earlier about is there a way to maybe stave off this kind of hormone change? We can't, but we can fix the pie graph, which is why I say that weight training.
Mel Robbins (00:58:40):
Okay, I have a crazy question
Jessica Shepherd (00:58:41):
Ask.
Mel Robbins (00:58:43):
Is anybody researching whether or not it's possible to have women continue to have a period for the rest of their life? I love this. Most women listen, like love this. I don't want to have a period for the rest of my life, but I literally, like if I will have no brain fog and I'll keep my muscles and there's no flesh fanny pack down there and I'm not an irritable bitch, I would take a period.
Jessica Shepherd (00:59:06):
Actually there is research that is actually mentioned in generation M of how do we prolong, not necessarily the period, how do we prolong the durability and duration of estrogen, right? We talked about that gap,
Mel Robbins (00:59:20):
Your own estrogen versus hormone replacement therapy.
Jessica Shepherd (00:59:23):
Correct. How do we keep the ovary alive in the sense of allowing it to still emit estrogen on its own? And that's where the research is really looking at because what did we say? There's a gap life expectancy because estrogen was down, now we're living longer. If we could fill that gap with having estrogen around naturally, then there is a likelihood that we would start to see decline, health outcomes, decline in heart disease, decline in osteoporosis, decline in dementia, and that would be an amazing innovative way for us to have better quality of life, even though we're living longer,
Mel Robbins (01:00:01):
Have they done any studies? And I realize hormone replacement therapy had issues because if I understand it correctly, when it first came out there was a bunch of junk science that has been disproven that scared people. And now all of those old claims have been basically refuted, refuted. And so for the vast majority of women, it is a extraordinarily safe and life-changing medical option. And for women who have a certain risk of cancer or a certain health history, it is not an option. But given the limited scope of wide range use, has there been any research that suggests that women that are candidates for hormone replacement therapy and who do take it have lower risks of dementia and osteoporosis and heart disease?
Jessica Shepherd (01:01:00):
Absolutely. So I'm glad we are in this day and age in science where we can definitely say that there is an impact in how women live their lives and decreasing their risk of death in osteoporosis. I'll start with osteoporosis because when we actually look at the recommendations, even from the Menopause society, which when they say if you take HRT, this is what it's going to help with. Now we know that it helps with the symptoms of menopause, hot flashes, night sets, et cetera. But when we look at bone health, it is actually proven that estrogen impacts bone health in a good way, obviously. But it's not our first line of therapy. They haven't said it's a first line of therapy. If someone comes in and they're like, I have osteopenia, which is weakening of the bone that I should say, you should automatically go on estrogen, but we know it helps. So that is there for osteoporosis. Now, dementia, brain health, which to me is fundamentally one of the biggest parts,
Mel Robbins (01:01:54):
But hold on, lemme ask a question. So if we know though that when there is a complete drop off of estrogen that it spikes a woman's risk for osteoporosis, it doesn't take somebody, no offense to people who are just wildly brilliant like you are, but common sense it tells you clearly there's a connection because we don't clear connection, don't see women in their thirties getting osteoporosis.
Jessica Shepherd (01:02:22):
Absolutely. Which is why I think that's where we need to challenge.
Mel Robbins (01:02:25):
I'm like, why on earth wouldn't you
Jessica Shepherd (01:02:26):
Medical societies, absolutely
Mel Robbins (01:02:28):
Immediately put somebody on estrogen if they're a candidate for it, if they are starting to decline in bone, that just seems like stupidity.
Jessica Shepherd (01:02:36):
I would actually echo exactly what you're saying because even in the clinical space, we need to do a better job at saying, we know this. This is data and we should be encouraging our patients to consider. Because the goal is not to say that everyone has to be on it like it's mandated, but to give you the data, the literature so that you know the reason why and you get to make that decision for yourself. But if I'm not giving you that information or that choice, you may not even know to make that decision for yourself.
Mel Robbins (01:03:05):
Let's talk about dementia. What does the research say about the impact of hormone replacement therapy, giving women estrogen and the outcomes with dementia?
Jessica Shepherd (01:03:17):
Now, that was one of the studies when they looked at the WHI, which is 20 years ago, and now we have so much better research that links estrogen depletion and decline. And what that does for later on in life when we look at dementia. So I'll give you numbers that make sense. When we look at Alzheimer's and neurodegenerative diseases, 70% of those cases are women. So clearly there's a link between why are women getting this more than males? And the answer is because when we look at that sharp estrogen decline, estrogen is one of the best anti-inflammatory substances in our body. So when we lose estrogen, we have an increase in inflammation, and that inflammation causes our neurons to have hardened plaques which lead later down the line because the course of how it builds and how it shows up is as much as 30 years. So that's why you start to see women having dementia in their seventies and eighties, but the process started back in their fifties. Why? Because of estrogen decline.
Mel Robbins (01:04:20):
Wow. Yeah. Can you share just the data on HRT? Because when you're in perimenopause, are you a candidate for HRT?
Jessica Shepherd (01:04:33):
This is one of the biggest questions now that we see in hormone replacement therapy in perimenopause. What we used to do, and this is again when I was training, which was about 15, 18 years ago, is that we would wait till women reached menopause. It's like they almost had to prove it. They would come in buckets of sweat and I would be like, well, when was your last period? And they're like, well, it was five months ago. And I'm like, so sorry. Can't offer you HRT. We have now gotten into a day and age where we know if you're hormones are declining and fluctuating and you're having a symptom, I absolutely should be offering you hormone replacement therapy as something Of course, wouldn't we? It's a car analogy. Again, why am I going to wait until there's no more car or more gas in the engine, but I'm still plugging away? Why wouldn't, when the indicator comes on, why would I not say this is a great opportunity for me to get gas? It's the same thing with hormones. Why are we depleting ourselves? Why are we allowing women to feel their absolute worst before we will offer them something that is going to help how they feel and their vitality?
Mel Robbins (01:05:38):
So what about women who are not candidates for it? What are their options?
Jessica Shepherd (01:05:43):
So their options. So there are actually a lot of options. Well, maybe not a lot, but there are options. And so coming from a day and age when there were no options, I think that it's really amazing that we are able to offer that. I think that the list of who cannot take hormone replacement therapy is probably good to go over so that everyone can make sure that if I am or not, I need to know.
Mel Robbins (01:06:03):
Great.
Jessica Shepherd (01:06:04):
So this would be someone who has a personal history, they themselves have had breast cancer and specifically a hormone receptor positive type of cancer responds to hormones. So the reason why I kind of double down on personal history is that there is a lot around breast cancer when we think I've had a family member, a cousin, an aunt, that doesn't put you in the same category as having a personal history of breast cancer.
Mel Robbins (01:06:32):
So not all breast cancers are the same. Correct. And just because you've had breast cancer doesn't mean you're automatically not a candidate for HRT.
Jessica Shepherd (01:06:41):
It's a very nuanced conversation and you definitely should be talking to your doctor specifically about what type of cancer that you've had, the course of cancer that has taken on your life, but also the age of when you were diagnosed and what that means. And the second thing is, if you've had a pulmonary embolism, you've had a clot in your lung, or even if you've had maybe a very large event of a clot somewhere else in your body has to be pretty significant for you not to be a candidate for hormone replacement therapy.
Mel Robbins (01:07:13):
And why do those two things make you not a candidate for hormone replacement therapy?
Jessica Shepherd (01:07:19):
That's a great question. Because of the hormones and the response of the body, whether it's the clot or the breast cancer that introducing hormones again may precipitate or cause another event like that.
Mel Robbins (01:07:30):
Gotcha. So based on your personal history, and there's a narrow window of women who have a particular type of personal breast cancer that may make them not a candidate, or if you've had a certain type of pulmonary embolism that you're not a candidate in those cases because the introduction of hormone might stimulate that condition coming back.
Jessica Shepherd (01:07:52):
Yeah, got it. Until for a clot, you may get another one, and for breast cancer may cause recurrence.
Mel Robbins (01:07:56):
Got it. Okay. But even I think there's also this widespread belief that if you've had any breast cancer history or if you've yourself have had breast cancer automatically, you can't do it.
Jessica Shepherd (01:08:07):
Yeah. Because a history of has your family had it and been exposed to and what was that and why do you have a genetic predisposition to that same cancer in your family? So again, that should be where that list is being kind of narrowed down when you talk to your doctor. But I want women to, even if they have a family history, that's where the conversation starts. Because if you just Exactly. I've had so many women who are like, oh, I can't do it, then they just never talk about it. And I'm like, but what if you found yourself that you can be exposed to it? Wouldn't that be great?
Mel Robbins (01:08:39):
Is there an age where it's too late to start hormone replacement therapy?
Jessica Shepherd (01:08:42):
This is another beautiful question because for a long time from that WHI study 20 years ago, we used to say, you can't start hormones if you've started 10 years after your last period, which is clinically menopause
(01:08:57):
Or after the age of 60. And so we have shifted those quite frankly. And again, it's a nuanced conversation, but there are plenty of women and we know it's safe to start after the age of 60 and also more than 10 years after menopause. Especially that last one I just said, because what if you experienced menopause at 42 45, which is not typical, but what if you did, and now you're 55 hearing us today, and you're like, well, it's 10 years I can't start hormone replacement therapy. Absolutely. You should be in your doctor's office saying, is this a possibility for me?
Mel Robbins (01:09:32):
Well, if you've already pushed through that window, so you have not had a period for years and you've just muscled your way through this, you're driving that car down the road, no gas in the tank, pedal to the metal, you're exhausted all the time. What might happen if you introduce hormone replacement therapy now?
Jessica Shepherd (01:09:58):
You know what might happen? You might feel better. Really? Yeah. There's so many women who, again, going back to the I'm going to numb. I'm not really feeling that, but you are. And so many women, once they get on hormone replacement therapy, that exact example that you gave, 55-year-old who maybe went 10 years,
Mel Robbins (01:10:16):
I'm even thinking the 60-year-old or the 62-year-old who was like, oh, well, it was still taboo and it's too late for me now.
Jessica Shepherd (01:10:24):
Yeah, a lot of women don't understand how they could feel because we subject ourselves to feeling, I don't feel great, but I'm just going to keep going. And the other thing that we talked about, what do we say? Osteoporosis, heart disease. So it may not have the same effect. I will make that statement, if you started hormone replacement earlier,
Mel Robbins (01:10:42):
But it might have a preventative effect, it might also get rid of the brain fog. It might help you sleep better.
Jessica Shepherd (01:10:50):
Lemme give you an example. I had a patient who came in and again, nuanced conversation, she was 67, but she was still having hot flashes, which is again, not typical because usually they'll wane and they'll go down in your fifties. She was still experiencing them to a way where it was impacting her quality of life. So I did have that conversation with her. She was very nervous, and I said, well, here's what we'll do. Why not give yourself the chance? What if we just trial and see how you feel after three to six months? She's still on it.
Mel Robbins (01:11:23):
How did she feel?
Jessica Shepherd (01:11:24):
She felt amazing. She was like, why was I living like this for so long? Yeah,
Mel Robbins (01:11:29):
Wow. I think I hear somebody hitting share right now and sending this to their mother and to their aunt, and to so many women who honestly were not served the medical care that they deserved
Jessica Shepherd (01:11:49):
And the diligence. And I think the conversations, because someone else could walk in behind her who's the same age or even maybe younger and we're like, maybe you're not the candidate, but we had the conversation. But if you're not having the conversation, then there's nothing to talk about.
Mel Robbins (01:12:02):
And maybe you are a candidate and maybe you could feel better. And wouldn't that be absolutely incredible? Wow. What are other tools in addition to hormone replacement therapy that women need to understand?
Jessica Shepherd (01:12:20):
I think that this is where when I talk about grieving, the loss of what we used to be.
(01:12:27):
That's where the mind and body come in. And so being able to modulate how our body functions has a lot to do with what we give it. And so giving it that loving care with looking at our diet, but also alternatives, which I advocate for all of my patients, is things such as mindfulness, meditation, how do we take the brain and allow it to not be as jittery and overprocessed and overstimulated comes with how we are able to teach it to quiet down acupuncture. Tai Chi has actually been shown in study to help decrease some hot flashes and night sweats, vasomotor symptoms for women. And even if you think of the culture of Asians, Asian women, if you look at a study, they had their vasomotor symptoms and menopausal symptoms for shorter duration and not as intense.
Mel Robbins (01:13:16):
What is a vasomotor? What'd you call it?
Jessica Shepherd (01:13:18):
Hot flashes and night sweats.
Mel Robbins (01:13:20):
That's the fancy word for it?
Jessica Shepherd (01:13:21):
That's that's the fancy word for those two.
Mel Robbins (01:13:24):
So my husband was like, you just soak the sheets. I'm like, I'm having my vasomotor.
Jessica Shepherd (01:13:27):
Absolutely. And so when you look at
Mel Robbins (01:13:29):
Sounds sexier too,
Jessica Shepherd (01:13:30):
Doesn't it? Yes. It doesn't make it so you're like, that doesn't sound, I'm having a vasomotor symptom is that they have shorter duration, decreased intensity, and a lot of that has to do with their lifestyle, their practice, what they eat, what they consume, but how they live their lives and also the practices that they do with movement of their body and being able to create the mind and the body throughout this whole transition.
Mel Robbins (01:13:54):
So there's no way to actually naturally recreate estrogen by lifting weights or taking supplements or doing that kind of thing.
Jessica Shepherd (01:14:05):
No. It's kind of like you're hijacking and bypassing the actual decline in hormones, but using the other parts of the body to elevate those and to optimize those parts of the body to offset what's going on biologically with the hormones.
Mel Robbins (01:14:21):
So I see. So the exercise and the stress reduction and the change in the diet forces your body to make new connections and workarounds in the place of the role that estrogen played.
Jessica Shepherd (01:14:37):
So using your body,
Mel Robbins (01:14:38):
So if you exercise and you get that incredible flood of neurochemicals, I think they call it after you go for a walker, after you lift weights or after you do that yoga class that works its magic in your brain and helps a little bit with the brain fog
Jessica Shepherd (01:14:56):
Right because our dopamine and our serotonin, our neurotransmitters, which when we see depression, they are decreased.
Mel Robbins (01:15:03):
Okay,
Jessica Shepherd (01:15:04):
You just said when you exercise, you get that flood of dopamine, you get that increase in serotonin, which is going to elevate her mood in lieu of losing hormones.
Mel Robbins (01:15:13):
Dr. Shepherd, could you talk to us about sleeping? Every one of my friends is having trouble sleeping. Every woman I know in their forties or fifties, and I have a particular person that I love who has what she calls her little helper, her Advil pm. I'm like, you got to stop taking that. She's like, but I'm taking my melatonin, I'm taking my progesterone and I got my cooling sheets. I still can't sleep. What is going on with hormones and sleep?
Jessica Shepherd (01:15:40):
I'll name three that are really categorical two sleep. And the reason why sleep is so important, let's lay the foundation, is that sleep actually is critical for our body in repair and recovery. And if our body's not able to do that, then it cannot function well. So when people have sleep disorders or sleep issues,
(01:15:56):
These are the people that we see later getting obstructive sleep disorder, heart disease, asthma, and also increase in obesity. So all things that are going to continue to decrease in quality of life. So now that we have that foundation of why sleep is so important, the three hormones that are crucial for that are going to be your estrogen, your progesterone, and your cortisol. And your cortisol, which I'll start with, has to do with your circadian rhythm, the reasons why we sleep, why we should sleep certain times. And cortisol has releases throughout the night, usually in the midnight and then early in the morning around 5:00 AM. So if your cortisol, remember these are chemical messengers that work on a timeframe if they're disrupted.
Mel Robbins (01:16:38):
And cortisol is highly impacted by your lifestyle and the stress factors
Jessica Shepherd (01:16:42):
Stress life and estrogen as well. So the estrogen decline now gives you hot flashes and night sweats. So now you're waking up at the middle of the night having a night sweat. So then your circadian rhythm, which was impacted by cortisol, is also taking a hit. It's deregulated and you're not getting good sleep quality. And then progesterone progesterone's the comfy hormone. It likes to relax us. It likes us to kind of settle down and feel good. And so we're also having fluctuations in progesterone, so it can't do the job that it really would like to do, which was give you sleep, quality and relaxation. So all of these different turns and declines, and it's impacting our sleep, which then impacts our health. And that's why we're starting to see that sleep or sleep health rather is so imperative and we need to pay more attention to our sleep.
Mel Robbins (01:17:28):
So what do we do?
Jessica Shepherd (01:17:29):
Yeah, so this is where we look at repleting, maybe our hormones, hormone replacement therapy can be a vehicle or a tool to kind of get you back to where you need to be hormonally. But then also we can look at practices a lot of times during that kind of deregulation or brain, a lot of women will say, my mind just races at night.
Mel Robbins (01:17:47):
What should we do?
Jessica Shepherd (01:17:48):
Ruminating? So decreasing rumination is where we need to do our work, our homework with quieting the brain down. So that is going to be your meditation and your mindfulness taking the screen away before you go to bed. I'm talking to myself as I say that. And then the other thing is actually when we look at CBD and what it's able to do as well has been helpful. It is very important, and I'll say this candidly, you have to know where you're sourcing it from. CB, D, we have endocannabinoid receptors in our bodies, which also contribute to relaxation is that you have to appreciate where it's being sourced. And then seeing is it have CBN, which is another part of the plant that actually helps with relaxation. So that's another way as well. So mindfulness, that's our homework, making sure, what are you eating? There are foods that are going to be inflammatory and going to kick off that cortisol. So decline in alcohol, decline in processed foods and sugar.
Mel Robbins (01:18:44):
You're fired Dr. Shepherd. I'm just kidding. It's true.
Jessica Shepherd (01:18:47):
And it's not fair.
Mel Robbins (01:18:48):
No, it's true. If you want to get a good night's sleep, don't even have a glass of One of the things though is do you believe as a medical doctor that you can through some of these lifestyle changes, boundaries with your phone, not looking at your, not even having your phone in your bedroom, having more of a set schedule, all the stuff that experts recommend, mindfulness. Do you believe you can train yourself to be a better sleeper if you get serious about it?
Jessica Shepherd (01:19:21):
Absolutely. I've seen it through and through. I think that even in my personal life, I was starting to see sleep disturbances and I had to take a real hard stop and being like, what's really going on? And taking that time to again, reflect on yourself, and I think that is self-care is sometimes self-care. Yeah, can be getting a manicure or a pedicure, but how am I going to take care of myself requires peeling away the layers of saying, am I contributing to the best version of myself or not? And what are the ways that I can do that? And am I going to pay attention to myself?
Mel Robbins (01:19:54):
Let's talk about the thyroid. It seems like a lot of people talk about having a thyroid issue. What does the thyroid do?
Jessica Shepherd (01:20:03):
The thyroid is this cute little organ that is the metabolic kind of engine of our bodies. It really is the we are going to go at this pace. At this rate, we're going to make things go quick. We're going to make things go slow. Which is why when people have hypo, which is less levels of that thyroid hormone, things are moving slower, typically they'll gain a little bit more weight, they're a little bit more sluggish, have fatigue syndromes. And then people who have too much of that thyroid, they're doing things too fast. It's like this metabolic train is really pumping. It's like the speed train and you're slow it down. So the goal is to keep it in that range where everything is moving. It's kind of like, is that the Goldilocks? A little bit too much, a little bit too little, just enough. So we want it in that just enough phase.
Mel Robbins (01:20:53):
So the thyroid, which is basically setting the pace, it's either going too slow, hypo or too fast hyper that it impacts hormones because it impacts the rate of release,
Jessica Shepherd (01:21:10):
The rate of release, and how quickly things should be going or how slow they should be going. And so when we start to see, you can have heat intolerance if it's too much, and cold intolerance if it's too slow. So the goal really is to kind of keep it in that homeostasis. And so when that starts to shift, it is very interconnected with estrogen. And so we start to see a little bit more thyroid issues as women go through perimenopause and menopause because the estrogen is not there to talk to the thyroid.
Mel Robbins (01:21:40):
If you have a problem with your thyroid, how would you know it, first of all?
Jessica Shepherd (01:21:43):
Oh, that is one of the I would say that is one of the hormones we can definitely see on labs that something is too high.
Mel Robbins (01:21:49):
Like a blood test?
Jessica Shepherd (01:21:50):
Absolutely.
Mel Robbins (01:21:51):
Gotcha. And then how do you treat it?
Jessica Shepherd (01:21:52):
So you can treat it either through medication, depending on if it's severely too high or too low. That's when a patient needs medication to kind of get it to homeostasis. Then you do have people who have symptoms, and it may not be all the way out of that kind of normal range. That's how you can impact with diet. That's how you can impact with exercise as well. And so it's really important that you understand your body, if it's changing, if something is happening that doesn't feel right to you to make sure that you see your doctor, because the goal is not to wait until you're completely just feeling horrible. And then now we do have a problem is that if it's shifting in that normal range to too high or too low, but it's not quite disease state yet that we know that. And so that again, is the preventative portion of why we need to take care of our bodies before we hit that wall. And now we're in disease.
Mel Robbins (01:22:42):
I want to shift gears a little bit and talk about a few health conditions that women see. And have you, Dr. Shepherd, help us understand them. One is PCOS. Can you talk to us about what that is?
Jessica Shepherd (01:22:56):
PCOS is one of those, I wish it were termed differently. It stands for polycystic ovarian syndrome. So when we use the word syndrome in medicine, it has a variety of different things that contribute to the disorder.
(01:23:09):
So it's not just one specific thing. So the reason why it's a syndrome is because it relates to the amount of follicles in your ovaries may be increased. So your body's supposed to be doing a certain thing. So I'll give you an example. If it's supposed to say, I'm using arbitrary numbers here. If you're going to have five follicles in your ovary and that's what it does every month, and now someone has 20, that's different what it should do. So you're going to have kind of these fluctuations of hormones. So now we're back to the hormone part of the syndrome, which is we usually see an increase in testosterone. So everything is supposed to be at the level it's supposed to be. So now if testosterone's a little bit higher, it's going to be sending messages not in the way or the amount or frequency that it should be.
(01:23:53):
So there's another thing is how we have our cycles. So you start to see your cycles be more irregular. I've had patients who have severe PCOS and they won't have a period for nine months or a year, and then they'll get one just randomly. So you have all these changes that are ovarian in nature, but the real heart of PCOS is actually a metabolic disease. So I'll go back to what metabolic means is really the function of how your body is doing internally. Usually from a glucose and an insulin perspective, we spend so much time doubling down on the ovaries malfunctioning, and it's an issue there. And we got to, but really a lot of it has to do with gut health, nutrition and insulin and glucose.
Mel Robbins (01:24:33):
But do you typically treat it by birth control or how do you typically,
Jessica Shepherd (01:24:38):
I would say that's what we typically treat it with. Am I a fan of what we typically treat it with? No, because then we're just focusing on the ovarian portion of it. So many of my patients, I work with functional nutritionists, but I also use that timeframe to saying maybe, so for example, now put you on A GLP, which can then impact your insulin and glucose and then shift the body's ability to function the way it should.
Mel Robbins (01:25:03):
Oh, that's so cool.
Jessica Shepherd (01:25:04):
Yeah.
Mel Robbins (01:25:05):
Wow. So GLP ones are a medical tool to help balance hormone and regulate hormones?
Jessica Shepherd (01:25:13):
Absolutely. Well, to balance the insulin and glucose and the metabolic health portion of PCOS. And a lot of times the diseases that we have are from a metabolic perspective. And so that's why when we look at the studies now with GLP ones, yes, you get the benefit of weight loss or people are on it because they're diabetics. But when we look at the whole body as this beautiful machine and how insulin and glucose can actually shape or maybe not help some of the functions of the bodies, when you're able to again, get it back to where it's supposed to be, the rest of the body is like, thank you. Now I can do what I need to do.
Mel Robbins (01:25:47):
Wow.
Mel Robbins (01:25:48):
Let's talk about endometriosis.
Jessica Shepherd (01:25:50):
Yes.
Mel Robbins (01:25:50):
What is it and what are signs that you may be at risk for it or that you have it?
Jessica Shepherd (01:25:56):
So endometriosis, which is, I'm so glad I spent 10 years being a minimally invasive gynecologist. The patients we would see mainly were endometriosis patients, is that it is when the lining, so when we have our uterus, we have that little kind of cavity within our uterus, which is where we shed endometrium in the lining and we get our period.
Mel Robbins (01:26:16):
So endometrium is the medical name for the thing that ends up on the pad.
Jessica Shepherd (01:26:21):
That's it.
Mel Robbins (01:26:21):
Wow. Okay.
Jessica Shepherd (01:26:23):
I love that you just put that perspective to it, but that's exactly what it is. And so when you shed the lining, that lining is only supposed to be there in that cavity. What happens is when that tissue may go somewhere else, it could go on the bowel, could go on the uterus, it could go on the bladder.
Mel Robbins (01:26:41):
Wait what do you mean that tissue goes somewhere else?
Jessica Shepherd (01:26:42):
So it kind of trails and ends up in other places in the abdominal cavity.
Mel Robbins (01:26:47):
So it's almost like your lining that makes up what is your period starts to flake and float around other parts of your body.
Jessica Shepherd (01:26:55):
It can kind of travel in other places really. And when it gets to those places, it causes pain. Most common symptom of endometriosis is pain and also infertility, right? Because it's impacting the other organs in the reproductive system. Now we do know that there are, it's an underdiagnosed disease. One in 10 women will have endometriosis, one in 10, one in 10. They may not experience it the same, but we are under diagnosing it. And the other thing is that there is somewhat of a genetic predisposition or a likelihood of getting endometriosis. If you had your mother and or sister have endometriosis,
Mel Robbins (01:27:31):
How do you treat it?
Jessica Shepherd (01:27:32):
The best way to treat it is to look at it from the root cause, which is estrogen. So if we are able to say, how can we decrease the level of estrogen that's creating this inflammatory response? So there are many ways that we can do that. Some people are put on birth control. Remember we talked about suppressing.
(01:27:50):
We can also use medications that are specifically designed to decrease estrogen specifically for that reason for endometriosis. And then some people need surgery, and the reason they need surgery is because it creates these kind of adhesions or these kind of scar tissue in the pelvis. And so that can cause the pain and or infertility. And we can go in there as a minimally invasive surgeon and get those kind of nodules and adhesions out, and that's how the patient can feel better. So there's a lot of different ways that we can actually impact endometriosis, which is why we should be talking about it more.
Mel Robbins (01:28:27):
Definitely.
Mel Robbins (01:28:28):
Chapter nine of your bestselling book, generation MI love the title, thin skin, thinner Hair. Let me read a little from page 169, dry, irritated skin bruises, breakouts, too much hair where you don't want it, your face too little hair where you do want it, your head. These are just some of the changes. Fluctuating hormone levels can unleash on your appearance. And this is no matter what age you are. And this was fascinating to read that estrogen spurs the growth of collagen, a protein that helps support skin, muscle and bones. It's essentially the scaffolding that holds everything up. So let's talk about the role of hormones with your skin and with your hair. Where do you want to start?
Jessica Shepherd (01:29:17):
I want to start with skin because we all know when we're in our younger ages that our skin is very kind of, it glows. It has this ability to not have wrinkles. And so as we start to age, which is a biological feature of what we're going to go through, decline in estrogen can't then go to that part of our skin that impacts the collagen, which gives us our ability to be plump, to be firm. And so what do we start to see as we age is decline in estrogen now, can't support
(01:29:53):
The collagen, which is the framework of that structure and the ability for a skin to do that. So another example is pregnancy. In pregnancy we usually see, which is a different type of estrogen, but it's a severe increase because that's what supports the pregnancy. A lot of women will say, my skin and pregnancy and my hair and pregnancy is just phenomenal. And the reason is is because there's this amazing estrogen support when the baby comes out and the estrogen declines, a lot of people are like, now I'm losing my hair or my skin is really, really crappy. That has to do with that balance of estrogen. So now when we're losing estrogen at a decline and it's not coming back, the skin responds. It's like estrogen's on around. I can't be plump. I'm going to have these wrinkles. My skin is starting to sag a little. And that's because of the estrogen can contribute to the collagen, which is scaffold.
Mel Robbins (01:30:42):
Gotcha. So is there anything that you can do to improve collagen skin? Yes.
Jessica Shepherd (01:30:50):
So it's the way that you can do it directly on your skin, which is when now we start to hear more about estrogen creams that you can apply to your skin
Mel Robbins (01:30:59):
And then that stimulates collagen growth.
Jessica Shepherd (01:31:01):
So it's the collagen growth, but also the blood flow. Estrogen is a very big proponent of blood flow and vascularity to areas. And that's what we need in order for a skin to look plump and not have the issues that it has in addition to the collagen. Yes. And so then the other part of that is if a woman is on hormone replacement therapy and she's either taking a pill, a patch, a cream, she's now giving her body back that estrogen, which allows it again to have the replenishment of estrogen, which supports our skin.
Mel Robbins (01:31:33):
Amazing. Women get marketed to crazy, and particularly for those 20 and 30 year olds that are buying 50 products and going through a 30 step skincare routine, Dr. Shepherd, based on the research, what actually in terms of the products can help your skin?
Jessica Shepherd (01:31:56):
I think that there is a lot of consumerism, so there's a lot of out there that are not necessarily going to get you the outcome that you want.
(01:32:04):
And so when we look at skin products specifically, I think as we're getting older, we need to look at products that have maybe retinol, Retin A that have things that actually are supporting collagen. Estrogen is one of those things, but it doesn't necessarily mean because something claims to get the outcome that you're going to do it. The other thing that I would say is we have to watch our diet. So what we're inputting into our body has a lot to do with what the skin is able to do, whether that's with foods that are supporting hydration, whether it's foods that's supporting vitamin deficiencies that have a lot to do with what we go through in menopause. But our gut, our gut health is always very impactful for how our skin can respond to
Mel Robbins (01:32:43):
What are the top foods you should eat for good skin?
Jessica Shepherd (01:32:45):
Oh, I think that top food should be obviously your protein intake, which can help your muscle, but also antioxidants. I love blueberries. I don't think that it's a power food and everyone just has to eat a blueberry, but what I do know is it has so many ways that it can fill your day, whether it's a snack, whether it's added to something that it has the antioxidants, which is also very helpful for our gut health.
(01:33:08):
And the last thing that I think is looking at how we use our omega fatty acids is an important part. So that would be in nuts. I think nuts are a great snack, but also salmon has omega fatty three acids as well. So that's important again for our gut health. And again, I think that when we look at our diet, not everyone responds. And that's why I don't love power foods is some people just don't respond the same way to certain foods. So making sure that you maybe talk to a nutritionist as you go through these stages in life because your body's going to respond differently and find out what's best for you and just don't take everything that you hear and saying that's going to apply to me.
Mel Robbins (01:33:43):
When you start going through perimenopause or menopause, do you need to change your skincare routine as estrogen plummets?
Jessica Shepherd (01:33:50):
You should really, yes, absolutely. Because the things that served your skin well when you're in your twenties and thirties are probably not going to serve it in the same way. One because of how our skin absorbs product is going to be different.
Mel Robbins (01:34:04):
How does it change?
Jessica Shepherd (01:34:05):
It changes where it's not as poor as porous just means if you were to think of a screen on a window and things that can go in versus come out,
(01:34:13):
Those things change because maybe it's more porous and it doesn't allow for the things that really should be staying in. It kind of seeps out. The other thing is that we have hot flashes and night sweats, so that increases the amount of sweat that is going to be around our face. And so that actually impacts it as well. And then we talked about the whole collagen and the estrogen, which is not there. So there is multiple layers of why the skincare should change. And things that I think are important to incorporate are, we talked about Retin a earlier, but also when we look at maybe using devices that get to a deeper level of our skin to help restore that vitality to our skin, but also helping correct some of the things on a deeper layer that we could never get to just from washing our face.
Mel Robbins (01:34:56):
Like what?
Jessica Shepherd (01:34:57):
Like lasers. I think lasers are a beautiful way that people should if they can, because sometimes they are pricey, but even if you have the opportunity to get a laser treatment, I think intermittently, those can again create this better foundation so that when we go home and maintain with other products, we're having a good foundation.
Mel Robbins (01:35:16):
Let's talk about thinning hair.
Jessica Shepherd (01:35:17):
Yeah.
Mel Robbins (01:35:18):
Because really
Jessica Shepherd (01:35:19):
It's real.
Mel Robbins (01:35:20):
It is real and it's very disconcerting. Why does our hair thin?
Jessica Shepherd (01:35:26):
Our hair has cycles. It has a growth phase, so it goes through these different cycles and estrogen is a very big part of those cycles and how long it's going to stay maybe in the growth phase. And so that's again, akin to when we were pregnant is we started to see a lot more hair growth. It stayed in that phase longer.
Mel Robbins (01:35:43):
So if I were to take folic acid, because you know how you take folic acid and then your nails and your skin, is that going to help me now?
Jessica Shepherd (01:35:49):
It will help you, but it's not going to solve the problem.
Mel Robbins (01:35:52):
What is the problem?
Jessica Shepherd (01:35:53):
I think that the problem is our decline in estrogen is not able to impact the hair follicles. It's not allowing to bring the blood flow to the hair follicles for growth, but also the growth phase. Because if estrogen is a big part of how long it's going to stay in the growth cycle of your hair, then when you're taking away estrogen, it can't stay in that phase forever.
Mel Robbins (01:36:14):
So if you're in your twenties or thirties and your hair is kind of thinning, should you also be looking very seriously at hormone balance?
Jessica Shepherd (01:36:23):
I would say hormone in the sense of thyroid. Thyroid is that, but also going back to our lifestyle factors. What are some environmental factors? Are you taking maybe medications that are contributing to hair? What foods are you eating and are you stressed?
Mel Robbins (01:36:36):
Wow.
Jessica Shepherd (01:36:36):
Yeah.
Mel Robbins (01:36:37):
And do any of those products that everybody is selling, you see all over those help?
Jessica Shepherd (01:36:41):
I think there are products that actually work. So for example, minoxidil. Minoxidil is an actual medication that's used for hair growth and helping in that hair cycle and maximizing the hair cycle, but also creating a vasodilation, which just means opening the vessels and allowing the blood to flow to that area more. So it does work. The caveat to that is when you're not using it, then it can't do the thing that it's going to do. So you may have some hair changes or hair growth cycle changes when you stop the drug.
Mel Robbins (01:37:10):
Wow, you are so brilliant and so fascinating. I have absolutely loved. I feel like I have learned so much today. I feel so empowered. I cannot wait to share this with every single woman I know, starting with my two daughters and my mother. I love that and all my good friends.
Mel Robbins (01:37:28):
What do you think Dr. Shepherd, the most important thing that you want women to understand about their hormonal health?
Jessica Shepherd (01:37:36):
I think hormonal health represents who we are as women. And the more that we vilify it or kind of fight against it, then that's not ultimately helping who we can be in our best version of ourselves. And so this transition really should be embraced and it really can herald the change in who we think of ourselves and identity in relationships and our power and our advocacy for ourselves. And so I don't want you to leave yourself behind. You should never leave yourself behind and bring yourself into this transition with your hormones in a way that it can be beautifully constructed to be the best version of yourself.
Mel Robbins (01:38:13):
If the person listening who's been with us today takes just one thing from everything you've shared and does something, what is it that you want them to do?
Jessica Shepherd (01:38:24):
I would say that the recreation of yourself requires that inner look into having self-care and self-love, because we all deserve it. And so as you go through transitions in your life, whether it's adolescence, whether it's pregnancy, whether it's menopause, those are moments in which you get to reflect inward and decide, what would I like to do for myself? And asking the important questions of who am I and where would I like to be?
Mel Robbins (01:38:51):
Dr. Shepherd, what are your parting words?
Jessica Shepherd (01:38:53):
My parting words would be that we all have this opportunity to change the journey of what we've been given, whether that's with circumstances, whether that's with our family life, whether that's with obstacles we go through to recreate and redirect who we are in our health. But our health really requires the ability to take a mind body connection. And many times we dissociate and we disconnect. And I would encourage anyone who's listening today and anyone that they can tell is that the importance of who we are in the end requires a MINDBODY connection. And I encourage everyone to take that opportunity to do that.
Mel Robbins (01:39:33):
Well, Dr. Jessica Shepherd, I cannot thank you enough. The bestselling book is Generation M, but what I love most about what happened today, at least for me, is the body connection is a critical thing. But because of everything you shared today, I actually understand my body in a way that I've never understood it before. And for that, I am so grateful, and I know I speak on behalf of the person who's listening and for all of the women in their life that they will be sharing this with. So thank you, thank you, thank you,
Jessica Shepherd (01:40:11):
Thank you.
Mel Robbins (01:40:12):
And I also want to thank you. Thank you for being here with us today. Thank you for being interested in your health and your happiness. Thank you for wanting to learn about this. Thank you for sharing this with all the women in your life that you care about. And in case no one else tells you, I wanted to be sure to tell you that I love you and I believe in you, and I believe in your ability to use this information today to better understand your health, to put yourself first, to know that you deserve better, and now that you understand how hormones work and how important they are that you use this information to improve your life and your health because you deserve that. Alrighty, I'm sure you're thinking. Alright, what do I watch next? This is the best video for you to watch next, and I will be waiting to welcome you in the moment you hit play. I'll see you there.
This is an evidence-based, practical guide that every woman needs for a healthy, vibrant life.
Finally, here is a fresh plan for a new generation entering perimenopause and menopause. With clinical insights, actionable tips, and holistic guidance, Dr. Jessica Shepherd, a board-certified OB/GYN and women’s health advocate, redefines how to sustain the marathon of this life stage so you can make the most of your health and vitality.
In Generation M, she throws out the old playbook and provides you with an empowering approach to thriving through this change and beyond.
Dr. Shepherd draws upon many conversations with leading experts in nutrition, meditation, and fitness, as well as with those living through perimenopause and menopause, who’ve shared what challenges them and what helps them live vibrantly.
In this book, you will find: Scientifically-backed information and advice from a doctor and menopause expert.
Evidence-based recommendations, tips, tools, and personal building blocks for the best health practices.
A guided exploration of new medical research and data
A deep dive on the safety and efficacy of HRT, including information on what medications to take and when to take them.
Holistic advice on how to ease your transition during this period, including recommendations for exercise, diet, sleep, mindfulness practices, and more.